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Applications chirurgicales et ambulatoires

Colle tissulaire Histoacryl®

Découvrez les avantages des différents types de colles tissulaires Histoacryl® pour les applications chirurgicales et ambulatoires. 

Colles tissulaires

Histoacryl®

The tissue adhesive Histoacryl® consists of monomeric n-butyl-2-cyanoacrylate, which polymerizes quickly in connection with tissue fluid.Histoacryl® is available in two colors:translucent, special for facial applicationblue, which enables an easy control over the quantity applied in different indications approved.Indication:Skin Closure: Closure of skin wounds without tension (including clean surgical incisions and incisions from minimally invasive surgery), and simple, thoroughly cleansed, trauma-induced lacerations.Sclerotherapy: Sclerotherapy of large esophageal or fundal varices.Mesh fixation: Fixation of hernia meshes, especially in inguinal hernia surgery.

Histoacryl® Flexible Pack

Histoacryl® Flexible is a sterile and liquid topical skin adhesive, consisting of n-butyl-2 cyanoacrylate and a softener to enhance flexibility. Its advanced formulation supports the closure of short and long incisions of up to 25 cm[1-3], making it suitable for use in a broad range of surgical procedures as well as in emergency care settings.It’s available in 2 versions:Blue version: For easy visual assessment of the layer that has been appliedClear Version: Specially designed for facial and cosmetic applications Histoacryl® Flexible may be used with an optional applicator tip intended to provide easy distribution of the adhesive over the wound, ensuring a precise & comfortable application.

Histoacryl® Octyl

Instruction for Use The incision or trauma site must be clean and dry before applyingadhesive. Ensure that the wound edges are easily approximated. (Fig. 1)Screw the Applicator Tip onto the threaded tube in a clockwise direction until the applicator is tight and seated on the tube. The applicator will puncture the foil membrane on the tube once seated and adhesive will be allowed to flow. (Fig. 2)Hold the Micro tube tip downwards, and the 1mm version horizontal. Gently squeeze the tube from the bottom until the adhesive becomes visible through the applicator device. Keep the device pointed away from the patient, until ready to apply the adhesive. (Fig. 3)While approximating skin edges, apply by squeezing the tube gently and continuously as you spread the adhesive back and forth over the wound site. Continue to hold the wound edges in approximation until the adhesive becomes tacky - typically less than 20 seconds. A smooth and even coat of adhesive is desirable. (Fig. 4)Once adhesive has completely polymerised (non-tacky) you may cover the site with a secondary bandage. If a secondary bandage is used, DO NOT apply to the adhesive area until it is completely tack free. Applying whilst tacky may result in adhesive removal when removing the secondary bandage and possibly dehiscence of the wound site. (Fig. 5)Discard adhesive device according to normal protocol after use. (Fig. 6)

Histoacryl® LapFix Pack

Histoacryl® LapFix Pack is a tissue adhesive applicator for laparoscopic hernia repair surgeries. It consists of a Histoacryl® LapFix-Cannula, a Syringe Injekt® 2mL Luer Lock Solo and a Histoacryl® ampoule.In recent years, atraumatic mesh fixation with tissue adhesive has increasingly become the method of choice. It is the recommended mesh fixation method by the International Hernia Society Guidelines for groin hernia management [1]. Histoacryl® Mesh Fixation is…AtraumaticStand-alone fixation method in different hernia repair techniques [2-10]Rapid polymerization [11]Atraumatic method reported to be better tolerated by the patient than traditional fixation methods [2-7, 9, 10, 12]Prevents complicationsReduced risk of post-operative pain compared to traditional fixation methods [2-7, 9, 12]Faster return to work compared to traditional fixation methods. [2, 4, 8, 13]Lower or similar intra- and postoperative morbidity compared to traditional fixation methods. [2, 4, 7, 9, 12]Lower or similar rate of infections related to Histoacryl® than other techniques [2, 4-6, 12, 14]Similar recurrence rate than with traditional fixation methods [2-9, 12]Easy to useDecreased surgery time compared to traditional fixation [4-6, 8, 12]Storage at <22 ºC [15]AffordableOnly necessary to apply few small drops to the desired fixing sites. [11,16]Lower price than tackers, fibrin glue or staples. [17] 

Documents

  • Onepager assortiment Histoacryl®

    Colles tissulaires pour les applications chirurgicales et ambulatoires

    pdf, 860.3 KB

  • Onepager Histoacryl® information pour le patient

    Tout ce que vous devez savoir après un traitement avec la colle cutanée Histoacryl®

    pdf, 1.6 MB

  • Certificat Histoacryl® superhéro

    Page à colorier

    pdf, 160.2 KB

  • Certificat Histoacryl® superhéroïne

    Page à colorier

    pdf, 163.6 KB

Références

Skin closure

1. Elmasalme FN, Matbouli SA, Zuberi MS. Use of tissue adhesive in the closure of small incisions and lacerations. J Pediatr Surg. (1995) 30:6 (837-8).

Surgical wounds

2. Dumville JC, Coulthard P, Worthington HV, Riley P, Patel N, Darcey J, Esposito M, van der Elst M, van Waes OJ. Tissue adhesives for closure of surgical incisions. Cochrane Database Syst Rev. (2014) Nov 28;(11)

3. Yulevich A, Cohen Z, Mares AJ. Use of N-Butyl-2-Cyanoacrylate (Histoacryl®) in Closure of Thoracoscopic an Laparoscopic Surgical Wounds in Children. Pediatric Endosurg. (1998) 2:1 (31-4).

Sclerotherapy

4. Feretis C, Dimopoulos C, Benakis P, Kalliakmanis B, Apostolidis N. N-butyl-2-cyanoacrylate (Histoacryl) plus sclerotherapy versus sclerotherapy alone in the treatment of bleeding esophageal varices: a randomized prospective study. Endoscopy. (1995) 27:5 (355-7).

5. Kozieł S, Kobryń K, Paluszkiewicz R, Krawczyk M, Wróblewski T. Endoscopic treatment of gastric varices bleeding with the use of n-butyl-2 cyanoacrylate. Prz Gastroenterol (2015) 10:4 (239–243).

6. Jang WS, Shin HP, Lee JI, Joo KR, Cha JM, Jeon JW, Lim JU. Proton pump inhibitor administration delays rebleeding after endoscopic gastric variceal obturation. World journal of Gastroenterology (2014) 20:45 (17127-17131).

7. Prachayakul V, Aswakul P, Chantarojanasiri T, Leelakusolvong S. Factors influencing clinical outcomes of Histoacrylglue injection-treated gastric variceal hemorrhage. World J Gastroenterol. (2013) 19:15 (2379–2387).

8. Lo GH, Lin CW, Perng DS, Chang CY, Lee CT, Hsu CY, Wang HM, Lin HC. A retrospective comparative study of histoacryl injection and banding ligation in the treatment of acute type 1 gastric variceal hemorrhage. Scand J Gastroenterol. (2013) 48:10 (1198-204).

9. Feretis C, Dimopoulos C, Benakis P, Kalliakmanis B, Apostolidis N. N-butyl-2-cyanoacrylate (Histoacryl) plus sclerotherapy versus sclerotherapy alone in the treatment of bleeding esophageal varices: a randomized prospective study. Endoscopy. (1995) 27:5 (355-7).

10. Tan PC, Hou MC, Lin HC, Liu TT, Lee FY, Chang FY, Lee SD. A randomized trial of endoscopic treatment of acute gastric variceal hemorrhage: N-butyl-2-cyanoacrylate injection versus band ligation. Hepatology. (2006) 43:4 (690-7).

Mesh fixation

11. Hoyuela C, Juvany M, Carvajal F, Veres A, Troyano D, Trias M, Martrat A, Ardid J, Obiols J, López-Cano M. Randomized clinical trial of mesh fixation with glue or sutures for Lichtenstein hernia repair. Br J Surg. (2017) 104:6 (688-694).

12. Hoyuela C, Juvany M, Carvajal F, Veres A, Troyano D, Trias M, Martrat A, Ardid J, Obiols J, López-Cano M. Randomized clinical trial of mesh fixation with glue or sutures for Lichtenstein hernia repair. Br J Surg. (2017) 104:6 (688-694).

13. Helbling C, Schlumpf R. Sutureless Lichtenstein: first results of a prospective randomized clinical trial. Hernia. (2003) 7:2 (80-4).

14. Kim-Fuchs C, Angst E, Vorburger S, Helbling C, Candinas D, Schlumpf R. Prospective randomized trial comparing sutured with sutureless mesh fixation for Lichtenstein hernia repair: long-term results. Hernia. (2012) 16:1 (21-7).

15. Testini M, Lissidini G, Poli E, Gurrado A, Lardo D, Piccinni G. A singlesurgeon randomized trial comparing sutures, N-butyl-2-cyanoacrylate and human fibrin glue for mesh fixation during primary inguinal hernia repair. Can J Surg. (2010) 53:3 (155-60

16. Kukleta JF, Freytag C, Weber M. Efficiency and safety of mesh fixation in laparoscopic inguinal hernia repair using n-butyl cyanoacrylate: long-term biocompatibility in over 1,300 mesh fixations. Hernia. (2012) 16:2 (153–62).